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@Kudasai yeah man....check this out. 

In 1935, however, American neuroscientists Carlyle F. Jacobsen and John Fulton presented the results of an experiment involving frontal lobe ablation in chimpanzees. Prior to ablation, one of the animals would become agitated when it made an incorrect choice during a memory task; this response was eliminated by the operation. (The other animal in the study experienced the opposite reaction; having been relatively docile, after ablation it experienced agitation during task performance.)

Also in 1935, Portuguese neurophysician António Egas Moniz headed a similar operation on a human. Moniz, who was affected by gout and could not use his hands to perform the surgery, enlisted the help of Portuguese surgeon Pedro Almeida Lima. The surgery consisted of drilling two holes in the patient’s head and then injecting pure ethyl alcohol into the prefrontal cortex. Alcohol was used to disrupt the neuronal tracts that were believed to give rise to and reinforce the recurrent patterns of thought observed in mentally ill patients. At the time, this first operation was considered a success, since there appeared to be a reduction in the symptoms of severe paranoia and anxiety that the patient had suffered prior to the surgery. Moniz and Lima subsequently performed the operation on a small subset of patients, refining the procedure as they went.

Edited by discolemonade
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