There were two Star Trek episodes that stand out.  In one, Captain Picard instructed a team to remove crystals from a planet for study, and later discovered that the crystals were alive and sentient.  In another, the ship encountered a cloud of gasses in space.  The gasses were alive.
 
	 
 
	Also, Kurt Vonnegut mentioned a life form that he described as, "I super intelligent shade of blue".  Yes, a living light frequency.